Tsinghua Holdings Co., Ltd. ("Tsinghua Holdings") is a solely State-owned limited liability corporation approved by the State Council. 

In September 2003, to incorporate enterprises under its control, Tsinghua University founded Tsinghua Holdings with a registered capital of 2.5 billion yuan ($395.13 million). In 2017, the company ranked No. 163 in China’s Top 500 enterprises by revenue and No. 7 by R&D efforts.

By making full use of Tsinghua University's scientific research advantages and skilled personnel, Tsinghua Holdings has been committed to the development path of industry-academia-research integration to meet both national and social demands. 

The company remains focused on innovation and technology services by insisting on its strategy of ecosystems, community, and global development. Driven by a combination of innovation, industry, and capital, it aims to help push ground-breaking ideas and findings from the lab into the market, incubate and invest in start-up tech companies, and make contributions to China's emergence as an innovation-driven country and to the transformation of its mode of economic development.

Tsinghua Holdings operates in five specialized areas: advanced technologies (integrated circuitry, environmental protection, and healthcare); innovation services; sci-tech finance; creative and cultural industries; and online education. It has a number of affiliated comprehensive groups such as Tongfang Co., Ltd., Tsinghua Unigroup, TusHoldings Co., Ltd., and Chengzhi Shareholding Co., Ltd.; as well as subsidiaries including Tsinghua Holdings Habitat Development Group, Tsinghua University Press, CapitalBio Corporation, Tsinghua Holdings Group Finance Co., Ltd., Tsinghua Holdings Nuclear, and MOOC-EN Education. In addition, it has fostered some leading companies in terms of industry segmentation, such as Nuctech, GSAFETY, cnki.net, THTI Holdings, and Tianjin Hwatsing Technology. 

To date, Tsinghua Holdings has held shares in many listed companies, including Tongfang Co., Ltd. (600100), Chengzhi Shareholdings Co., Ltd. (000990), Unisplendour Co., Ltd. (000938), Guoxin Micro, Tongfang Technovator (01206.HK), Tus-Guhan Group Corp Ltd. (000590), Neo-Neon Holdings Limited (01868.HK), Tus-Sound (000826), Tus International (00872.HK), and GSAFETY (300523). 

As a Tsinghua University's platform to serve society, Tsinghua Holdings has been working on bringing Tsinghua University's scientific and technological achievements to the market. The company has commercialized 56 national key scientific achievements and made breakthroughs in over 62 key technologies. It has promoted commercialization of three national science and technology major projects and has made remarkable achievements in technology innovation and technology transformation, with many having an international impact. 

Its achievements include the world's first high-temperature gas cooled reactor nuclear power plant; the freight container inspection system that enjoys the biggest global market share; China's first public safety and emergency response system with complete and independent intellectual property rights; China's first 12-inch CMP equipment; and the world first hereditary deafness gene test chip. 

Tsinghua Holdings is also the operator of the biggest university science park in the world and the first entrepreneurship street in China.